Reed Jobs Launches $200M+ Venture Fund Aiming to Turn Cancer into a Manageable Condition

By Sophia Reynolds | Financial Markets Editor

Reed Jobs, the 34-year-old son of Apple visionary Steve Jobs, is channeling both personal history and substantial capital into a bold mission: to fundamentally alter the trajectory of cancer treatment. His venture firm, Yosemite, has closed over $200 million for its second fund, with ambitions to raise an additional $150 million, positioning it to accelerate a new wave of oncology innovation.

The fund, which now manages more than $1 billion in total assets, boasts backing from a consortium of heavyweight investors, including biotech leader Amgen, the Memorial Sloan Kettering Cancer Center, MIT, and renowned venture capitalist John Doerr. This financial firepower will be directed at a portfolio of approximately 25 companies working on the cutting edge of cancer therapy.

"Our goal is to shift the paradigm for most cancers—from a death sentence to a chronic, lifelong condition," Jobs stated in an interview. "Given the convergence of technologies we're seeing, I believe this is an achievable vision within my lifetime."

Jobs's commitment is deeply personal. He was 12 when his father was diagnosed with pancreatic neuroendocrine tumor, a experience that shaped his early path. He worked in Stanford cancer labs as a teen and began college as a pre-med student. After his father's passing in 2011, he explored other disciplines but ultimately returned to healthcare through his mother Laurene Powell Jobs's Emerson Collective, where he led cancer-focused initiatives.

In 2023, he spun out Yosemite as an independent entity. The firm takes a broad, interdisciplinary approach, investing in gene therapy, cancer vaccines, radiopharmaceuticals, AI-driven drug discovery, and early detection technologies. "I never envisioned myself in venture capital," Jobs admitted. "But I realized that by incubating and shaping these ventures from the ground up, you can directly influence the scientific focus and the assets that get developed—that's where you can make a tremendous difference."

Yosemite's current holdings include companies like Tune Therapeutics, Azalea Therapeutics, and Chai Discovery. The new fund will continue to prioritize long-term, transformative science. "The timelines are significant," Jobs acknowledged, "but we're at a unique moment where multiple breakthrough paths are converging."

Industry & Public Reaction:

"This isn't just another fund. Reed is leveraging his unique position and network to de-risk and accelerate high-impact science that traditional VCs might shy away from. The institutional backing from MSK and Amgen is a huge validator."Dr. Anya Sharma, Oncology Researcher at a major university hospital.

"While the ambition is commendable, let's be real. 'Ending cancer deaths' is a headline-grabbing slogan we've heard for decades. Throwing money at the problem isn't the same as solving it. The real test will be in tangible patient outcomes, not portfolio size."Mark Devlin, Biotech Analyst & frequent industry critic.

"It's inspiring to see the next generation of leaders applying their resources and influence to such a critical cause. The focus on AI and early detection is particularly promising, as prevention and precision are key to changing the survival curve."Elena Rodriguez, Founder of a patient advocacy non-profit.

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